Understanding Asthma Treatments – Relievers and Preventers

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Millions of people around the world suffer from Asthma, a chronic lung condition characterized by difficulty in breathing. During an asthma attack, the sufferer's airways become irritated and react by narrowing and constructing. That causes increased resistance to airflow, and obstructs the flow of the air to and from the lungs.

How is asthma treated?

Asthma is treated using two main types of medicines:

* Quick Relief Treatments: also called relievers. These give rapid, short-term treatment and are taken when you have worsening asthma symptoms that, left untreated, can lead to asthma episodes or attacks. You will feel the effects of these medicines within minutes.

* Long-Term Control Treatments: also called preventers, and are for people with persistent asthma, who need long-term control medicines. Preventers are taken every day, usually over long periods of time, to control chronic (long-term) symptoms and to prevent asthma episodes or attacks. You will feel the full effects of these medicines after taking them for a few weeks.

Drugs related to hormones

Drugs, such as those resembling two of our hormones, can help treat asthma. These two hormones are epinephrine (adrenaline in the UK) and hydrocortisone (a steroid). Epinephrine is pumped into our bloodstream when we have a sudden fright or emergency psychologists often call this state fright or flight. Epinephrine is the quick-acting hormone from the middle of the adrenal glands near our kidneys. It makes your pulse race, your heart thump, and readies your body for emergency action. In asthma, the medicines which resemble adrenaline quickly relieve asthma for a short time, and are from the reliever family.

Hydrocortisone comes from the outer part of our adrenal glands, called the 'cortex'. It is also partly an emergency hormone but it works much more slowly, for much longer, and in a completely different way to adrenaline. Medicines which resemble hydrocortisone slowly allow the lining of air tubes in an asthma sufferer to become normal. As a result, your asthma becomes less severe and you are less likely to get asthma attacks. So these steroid medicines are part of the preventer family. Steroids are the most powerful preventers currently available.

Other long-term treatments include:

* Long-acting beta-agonists are bronchodilators, not anti-inflammatory drugs. These medicines are used to help control moderate and severe asthma and to prevent night-time symptoms. Long-acting beta-agonists are taken together with inhaled corticosteroids

* Leukotriene modifiers (such as montelukast, zafirlukast, and zileuton) are long-term control medicines used either alone to treat mild persistent asthma or together with inhaled corticosteroids to treat moderate persistent asthma or severe persistent asthma.

* Cromolyn and nedocromil are used to treat mild persistent asthma.

* Theophylline is used either alone to treat mild persistent asthma or together with inhaled corticosteroids to treat moderate persistent asthma. People who take theophylline should have their blood levels checked to be sure the dose is appropriate.



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